Protein Info for SM_b20370 in Sinorhizobium meliloti 1021

Annotation: ATP-binding transport protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 226 PF00005: ABC_tran" amino acids 23 to 172 (150 residues), 117.8 bits, see alignment E=6e-38

Best Hits

Swiss-Prot: 52% identical to LOLD2_CHLL7: Lipoprotein-releasing system ATP-binding protein LolD 2 (lolD2) from Chlorobium luteolum (strain DSM 273 / 2530)

KEGG orthology group: K09810, lipoprotein-releasing system ATP-binding protein [EC: 3.6.3.-] (inferred from 100% identity to sme:SM_b20370)

Predicted SEED Role

"Lipoprotein releasing system ATP-binding protein LolD"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92WI3 at UniProt or InterPro

Protein Sequence (226 amino acids)

>SM_b20370 ATP-binding transport protein (Sinorhizobium meliloti 1021)
MSPLIEARGLTRILHETVPVTLVKDIDLIIEEGEFVAVTGPSGSGKSSLLYLLGLLDRPT
EGRLRVRGRDTEPMSEKERAETRLATMGFVFQFHFLLPEFTARENVEIPMRKLARLGRDE
MRGRATDLLSSLGLADHLDKRPDQLSGGQRQRVAVARALANDPPLILADEPTGSLDSRSS
EQVFAILDGLVRERGKTVVAVTHDLDMAARMDRRIHLVDGEVSKEE