Protein Info for SM_b20356 in Sinorhizobium meliloti 1021

Annotation: sensory histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 917 transmembrane" amino acids 31 to 56 (26 residues), see Phobius details amino acids 201 to 224 (24 residues), see Phobius details PF00672: HAMP" amino acids 220 to 267 (48 residues), 39.3 bits, see alignment 1.6e-13 PF12860: PAS_7" amino acids 290 to 403 (114 residues), 64.1 bits, see alignment E=3.3e-21 PF00512: HisKA" amino acids 420 to 487 (68 residues), 75.9 bits, see alignment 5.1e-25 PF02518: HATPase_c" amino acids 535 to 647 (113 residues), 100.2 bits, see alignment E=2.5e-32 PF00072: Response_reg" amino acids 671 to 778 (108 residues), 75.8 bits, see alignment E=7.7e-25 amino acids 788 to 900 (113 residues), 65.1 bits, see alignment E=1.6e-21

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SM_b20356)

Predicted SEED Role

"FIG01074439: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92WJ7 at UniProt or InterPro

Protein Sequence (917 amino acids)

>SM_b20356 sensory histidine kinase (Sinorhizobium meliloti 1021)
MSALGHELRSTEAARPAKRLDSRITDLPISARVAALTAAGLISLVLSSLFLTQALYRSAE
RMAETRELFDRAASAASAHVAFGDLRYWLTDLSVSLLMNSQRNADEARERLQEQLAGLAK
HAPEAVEAIRTEVDAYVETALQAADSYTQDNRIVGNALLAKARTHSGKVDADLNRLVEQV
KAEAEAARNEVVVQTEKTATTAAILVGGVVLIGSLLTLLVLRSIVGPLRRLNRVIGDLTE
GRYDVDIPEEGGDELGAMARTLSLFRESAIEKKKLEDEAERQRRTIAAALEVISDGFVLY
DSEDRILVANSKYCEIFPSHKPNTLRGRSFREIVEQNLEMGQVDLEGKSPQEWVDERVRL
HRDPAGLVDEKRFGDKWVRISKRKIPDGGTVAVYTDITQLKQRQVELERAKSHAESANEA
KSRFLASMSHELRTPLNAIIGYSEMLIEEARDHEDEELVPDLDKIASAGRHLLSLINDIL
DLSKIEANKMEVFLETFSVADLLRDVAATVAPLMARNGNEFTQDFEADLGEMHSDQTKLR
QNLFNLLSNAAKFTNGGRVTLRVRREQRPDRDWLVFQVTDTGIGMSPEQQERLFNAFTQA
DASTTRNYGGTGLGLSITRSFCRMIGGVVTVESEVGKGSVFTMEVPAQCEREADGSPAEP
VPQVGSGRTALIIDDEPAARSLIAKALAEAGLASIEASNGQEGLAAARKHRPDAIILDII
MPHQDGWSVLRALKNDPELCTIPVILATILADRELGLSLGAVEYLTKPIDTDKLVRTIET
FGGGKHDVLVVDDDQASREFLRRILVKRKWTVHEAGDGIRGLEMMKRILPRLVLLDLLMP
EMDGFQTLSEMQRIPELQNIPVVVVTSKDLSASELKWLRDRAVAVVNKGANSRSQLVAAL
ERQIGSGASVGKALADG