Protein Info for SM_b20269 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 563 PF01989: AcnX_swivel_put" amino acids 7 to 132 (126 residues), 123.4 bits, see alignment E=9.6e-40 PF04412: AcnX" amino acids 151 to 327 (177 residues), 265.2 bits, see alignment E=4.2e-83 PF28403: AcnX_2nd" amino acids 332 to 426 (95 residues), 94.7 bits, see alignment E=4.9e-31 PF28406: AcnX_3rd" amino acids 436 to 550 (115 residues), 132.1 bits, see alignment E=2.1e-42

Best Hits

KEGG orthology group: K09123, hypothetical protein (inferred from 100% identity to sme:SM_b20269)

Predicted SEED Role

"2-Methylcitrate dehydratase AcnD" in subsystem 2-methylcitrate to 2-methylaconitate metabolism cluster

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92WS0 at UniProt or InterPro

Protein Sequence (563 amino acids)

>SM_b20269 hypothetical protein (Sinorhizobium meliloti 1021)
MSGLDPARSILQGSAEGPVIATGEALSFWGGVDPATGCVIDVHHPLHGVPLTGSILMMPS
SRGSCTGSGVLLDLVLTGRGPAALVFSEPEDVLTLGALIASEMFGKPLPVLRLAPEAFAA
LARAKTARIGDRAIEAEGLTIPVVPPATVALDLTDGDRAMLDGAESVAVAQAMRIISAMA
AQQGALGLVDVTQAHIDGCIYASPANLTFAEKMVEMGAKVRIPATMNAISVDHANWQRQG
VPPSFGDPAARLADAYVRMGCRPTFTCSPYLLDSAPGAGEAVAWAESNAVIFANSVLGAR
TAKHPDFLDLCIALTGRAPLSGVYLDEHRKARRIIDVELPAGADDAFWPLIGYLAGRAAP
DRIPLIRGLAPAEPSRDDLKALCAAFGTTSAAPMLHVEGVTPEAGGAAAEDADHATITRA
ELTAAWSALNEGPDEVELVAIGSPHASLAECRALAEALGGRKRHPDVAVIVTAGHEVIAK
ARGEGILARLQESGVQVLPDLCWCSISEPVFPTRTRAVMTNSGKYAHYGPGLSGRTVRFG
SLADCVSAALSGRVPPRLPEWLS