Protein Info for SM_b20218 in Sinorhizobium meliloti 1021

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 161 to 181 (21 residues), see Phobius details PF00672: HAMP" amino acids 180 to 230 (51 residues), 29.9 bits, see alignment 5.7e-11 PF02518: HATPase_c" amino acids 335 to 439 (105 residues), 86 bits, see alignment E=2.4e-28

Best Hits

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_3953)

Predicted SEED Role

"sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92WW6 at UniProt or InterPro

Protein Sequence (454 amino acids)

>SM_b20218 sensor histidine kinase (Sinorhizobium meliloti 1021)
MAARSILHGIHLWPRTLRARLFVILLAGLTIAHAMSFAALFSERYIAARSVMFNTLETDV
ATSIAILDRLPATERAAWLGRLERGSYRFVLGRGLPGSRVLNEVDVEVADKVRAAIGAKY
PIEVESIPGGVRRLQAHLRLSDGEPLTIDITPRGVMPVADWLPYVLVAQLSLLVLCSWFA
VRQATRPLADLAKAADTLDPNSRTPRLSETGPREVAYAATAFNAMRDRIAQYLEERVQIL
AAISHDLQTPITRMKLRAEMAEASIERDKLITDLDEVERLVKEGVAYARSAHGKDEKASR
IDLASFIESLAYDYQDTGKAVTVAELGDGAIVTRPHALRRILTNLIDNALKFGGSAEIEV
QRRPEGTVTIKVLDRGPGIPEDQLEAVLQPFFRLEQSRSRDTGGTGLGLAIAQQLATVIG
GSLTLRNRDGGGLAAELSLESSTVSMKQWNSLAL