Protein Info for SM_b20214 in Sinorhizobium meliloti 1021

Annotation: oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 267 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF08659: KR" amino acids 7 to 169 (163 residues), 46.6 bits, see alignment E=7.9e-16 PF00106: adh_short" amino acids 8 to 193 (186 residues), 150.9 bits, see alignment E=6.5e-48 PF01370: Epimerase" amino acids 9 to 138 (130 residues), 29 bits, see alignment E=1.4e-10 PF13561: adh_short_C2" amino acids 13 to 192 (180 residues), 97.3 bits, see alignment E=2.2e-31

Best Hits

KEGG orthology group: K07124, (no description) (inferred from 100% identity to smk:Sinme_3957)

Predicted SEED Role

"Short-chain dehydrogenases of various substrate specificities"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92WX0 at UniProt or InterPro

Protein Sequence (267 amino acids)

>SM_b20214 oxidoreductase (Sinorhizobium meliloti 1021)
MTQHSKGTALVTGASSGIGAIYADRLARRGYDLILVARNQTRLDQLARRLTDETGRSVEV
VAADLGKRTDAARIEKVLRTDASITMLVNNAGVGATGPLLASDVDKMEEMIALNVNALTR
LTYAAVPGFVARGSGAIINIASIVGIAPEVLNGVYGGSKAFVLAFTLSLQKELEGRNIRI
QAVLPGATATDFWGIAGTPVEHLPNEIVMPAEDMVDAALVGFDLGEPITIPSLPDAADWE
AYEAARQKLVPNLSLSVPAARYRAAAA