Protein Info for SM_b20209 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01361: Tautomerase
  • amino acids 2 to 63 (62 residues), 46.8 bits, E=1.1e-16

Best Hits

Swiss-Prot: 36% identical to Y924_HELPY: Probable tautomerase HP_0924 (HP_0924) from Helicobacter pylori (strain ATCC 700392 / 26695)

KEGG orthology group: K01821, 4-oxalocrotonate tautomerase [EC: 5.3.2.-] (inferred from 100% identity to smk:Sinme_3963)

Predicted SEED Role

"4-oxalocrotonate tautomerase (EC 5.3.2.-)" in subsystem Central meta-cleavage pathway of aromatic compound degradation (EC 5.3.2.-)

MetaCyc Pathways

• 3-chlorocatechol degradation III (meta pathway) (2/4 steps found)
• orthanilate degradation (2/5 steps found)
• protocatechuate degradation III (para-cleavage pathway) (2/5 steps found)
• catechol degradation to 2-hydroxypentadienoate II (1/4 steps found)
• 4-amino-3-hydroxybenzoate degradation (2/6 steps found)
• 2,3-dihydroxybenzoate degradation (1/5 steps found)
• catechol degradation II (meta-cleavage pathway) (1/7 steps found)
• meta cleavage pathway of aromatic compounds (2/10 steps found)
• 2,2'-dihydroxybiphenyl degradation (1/10 steps found)
• toluene degradation IV (aerobic) (via catechol) (2/13 steps found)
• superpathway of aerobic toluene degradation (9/30 steps found)
• superpathway of aromatic compound degradation via 2-hydroxypentadienoate (7/42 steps found)

KEGG Metabolic Maps

• Benzoate degradation via hydroxylation
• Fluorene degradation

Isozymes

Compare fitness of predicted isozymes for: 5.3.2.-

Use Curated BLAST to search for 5.3.2.-

Sequence Analysis Tools

See Q7ANT1 at UniProt or InterPro

Protein Sequence (79 amino acids)

>SM_b20209 hypothetical protein (Sinorhizobium meliloti 1021)
MPIVTVQVTREGSAPGRNSVTAEEKAAIIKGVSEVLLDVLNKPLESTYVVIEEVELDNWG
WGGFPTVQFRRQRAETARS