Protein Info for SM_b20049 in Sinorhizobium meliloti 1021

Annotation: elongation factor G

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 653 PF00009: GTP_EFTU" amino acids 49 to 249 (201 residues), 31.7 bits, see alignment E=2.2e-11 PF14492: EFG_III" amino acids 358 to 428 (71 residues), 37.6 bits, see alignment E=3.6e-13 PF03764: EFG_IV" amino acids 435 to 549 (115 residues), 123.3 bits, see alignment E=1e-39 PF00679: EFG_C" amino acids 553 to 640 (88 residues), 47.7 bits, see alignment E=2.6e-16

Best Hits

KEGG orthology group: K02355, elongation factor G (inferred from 100% identity to sme:SM_b20049)

Predicted SEED Role

"Translation elongation factor G-related protein" in subsystem Translation elongation factor G family

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92XB0 at UniProt or InterPro

Protein Sequence (653 amino acids)

>SM_b20049 elongation factor G (Sinorhizobium meliloti 1021)
MRCFTVLGPSQIGKSTLVERVGSLGGEPKKSVTPYGLGLTEFEFGGEAWCALDVPGNNEA
LAHAQHALLASDACVLCVSPILDEAVLAAPYLRMIEASGTPCILFINRMDEPRGRIRDIV
AALQDFCSRPLILRQIPIRDGDRIIGSCDLISERAWRYREGQPSSLFEIPESALEREHEA
RAELLEHLSEFDDWLLEELIEDREPASDAIYSISTRVLNENKIIPVLLGSASHGNGLMRL
MKALRHEAPRAEALKKRLAAGAGVDETTLLAVSFHAHYRQSVGKTVLARALQNGVKQGAT
LGGASLGALQDPASGRPIGSGVTEAGQLFGAVKSDHLPVPSLLTAGAAVAPPDWTTPPTP
MLERILVPASERDETKLSETLAKLAETDRGLKVMQEEGTGAQLVCAQGPVHLREVCRTLS
DVFHVEVSDRPPSPIYRETVSKSSDVHYRHRKQTGGAGQFADVKLSVHPNGRGDGFSFAE
TVKGGAVPRNYIPAVEAGAREAMEKGPLGFKVIDVGVLLTDGQHHSVDSSEYAFRTAGKL
GVRQALSQAASVLMQPVFRVEIHVPSVYSGSLVPIVASLKGQVLGFDRDEAAKGWDIFRA
LLPGSALDDLARSLRSATQGIGYFSKNFDHFEELYGKEAQAIVTAHGAPANEH