Protein Info for SM_b20046 in Sinorhizobium meliloti 1021

Annotation: replication protein A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 398 transmembrane" amino acids 256 to 274 (19 residues), see Phobius details TIGR03453: plasmid partitioning protein RepA" amino acids 18 to 397 (380 residues), 643 bits, see alignment E=7.4e-198 PF06564: CBP_BcsQ" amino acids 117 to 278 (162 residues), 30.8 bits, see alignment E=6.3e-11 PF13614: AAA_31" amino acids 117 to 294 (178 residues), 129.8 bits, see alignment E=3.4e-41 PF09140: MipZ" amino acids 118 to 158 (41 residues), 30 bits, see alignment 1e-10 PF01656: CbiA" amino acids 120 to 358 (239 residues), 91.2 bits, see alignment E=1.5e-29 PF02374: ArsA_ATPase" amino acids 123 to 285 (163 residues), 38.5 bits, see alignment E=2.4e-13

Best Hits

Swiss-Prot: 56% identical to Y4CK_SINFN: Putative replication protein A (NGR_a00010) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: None (inferred from 100% identity to sme:SM_b20046)

Predicted SEED Role

"Plasmid replication protein RepA" in subsystem Plasmid replication

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92XB3 at UniProt or InterPro

Protein Sequence (398 amino acids)

>SM_b20046 replication protein A (Sinorhizobium meliloti 1021)
MLQQRIQSLEEQEHLPSLLSADAQELAHQLQEHQKKIFSPSAQKTMRLFSPAEAAAFIGI
GEGYLRQIASEGHGPQPLSNGRRMYAMEDIDRIRRVLDEGSKTGKYIPHRRPGEKLQVVS
VMNFKGGSGKTTTSAHLAQYLALRGYRVLAIDLDPQASLSALFGHQPELDVGEGETLYGA
IRYEAPRPIAEVVRSTYTANLHLIPGNLELMEFEHETPKAMIAGSTETMFFARIGEVLSE
IESFYDIVVIDCPPQLGFLTMSALCAATSVLITVHPQMLDVMSMSQFLSMTSELMAVVEN
AGGRTSYDWMRYLVTRFEPNDGPQSQMTGFMRAIFGNRMLQNAMVKSTAISDAGVTKQTL
YEVERSQFIRGTYDRAMDSLSLVNAEIEEMIRRVWGRK