Protein Info for SM_b20040 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 signal peptide" amino acids 7 to 11 (5 residues), see Phobius details transmembrane" amino acids 12 to 27 (16 residues), see Phobius details amino acids 35 to 56 (22 residues), see Phobius details amino acids 67 to 88 (22 residues), see Phobius details amino acids 94 to 113 (20 residues), see Phobius details amino acids 122 to 139 (18 residues), see Phobius details amino acids 146 to 165 (20 residues), see Phobius details amino acids 177 to 197 (21 residues), see Phobius details amino acids 209 to 230 (22 residues), see Phobius details amino acids 237 to 258 (22 residues), see Phobius details amino acids 264 to 282 (19 residues), see Phobius details PF00892: EamA" amino acids 6 to 135 (130 residues), 50.5 bits, see alignment E=1.3e-17 amino acids 148 to 279 (132 residues), 52.9 bits, see alignment E=2.2e-18

Best Hits

Swiss-Prot: 68% identical to YDEK_BACSU: Uncharacterized transporter YdeK (ydeK) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_4130)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92XB9 at UniProt or InterPro

Protein Sequence (286 amino acids)

>SM_b20040 hypothetical protein (Sinorhizobium meliloti 1021)
MNKATSGWMSGLIGVVIFSGSLPATRVAVMDFDPIFLTVARATIAGILAFCLLFAFRERR
PARGDLASLAVISLGVVVGFPLMTALALRHVTSAHSIVFIGLLPLATAIFGVLRGGERPR
PTFWVFSGLGSAIVVGFAARQGFSASPIGDLLMLAAIVACGLGYAEGAKLSRRLGGWQVI
CWALVLSLPVMTALMLATMPSSLAGPSAASWLGFGYVSVFSMLIGFIFWYRGLALGGIVA
VGQLQLLQPFFGLALASTLLGENVSWSMLAATVAIVACVAGAKKFA