Protein Info for SGL_RS17685 in Synechocystis sp000284455 PCC 6803

Annotation: ArsB/NhaD family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 transmembrane" amino acids 6 to 22 (17 residues), see Phobius details amino acids 28 to 47 (20 residues), see Phobius details amino acids 54 to 74 (21 residues), see Phobius details amino acids 97 to 125 (29 residues), see Phobius details amino acids 135 to 157 (23 residues), see Phobius details amino acids 177 to 202 (26 residues), see Phobius details amino acids 223 to 241 (19 residues), see Phobius details amino acids 247 to 266 (20 residues), see Phobius details amino acids 279 to 298 (20 residues), see Phobius details amino acids 310 to 333 (24 residues), see Phobius details amino acids 340 to 360 (21 residues), see Phobius details amino acids 380 to 405 (26 residues), see Phobius details amino acids 424 to 445 (22 residues), see Phobius details PF03600: CitMHS" amino acids 18 to 359 (342 residues), 183.8 bits, see alignment E=5.1e-58 PF02040: ArsB" amino acids 18 to 434 (417 residues), 48.7 bits, see alignment E=7.6e-17

Best Hits

Swiss-Prot: 100% identical to Y753_SYNY3: Uncharacterized transporter slr0753 (slr0753) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: None (inferred from 100% identity to syn:slr0753)

Predicted SEED Role

"Arsenic efflux pump protein" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (449 amino acids)

>SGL_RS17685 ArsB/NhaD family transporter (Synechocystis sp000284455 PCC 6803)
MVANLPALFSLGVFVGVILLIMSEKIHLTIAAFLGALILVFTHVITLKEGIDYISQSYAT
LALFFGVMVLVRSFEPTKIFEYLATQMVLLAKGSGKLLMLGVIAITTPICAVLPNATTVM
LLAPLIPPLAQEIGVDFVPILILMVFVANSAGLLTLVGDPATFIVGDAINISFNDYLFKL
SFMGVLAIVSIVVITPFLFRHIWRSRFTHLEDLPHPQINHPKVLMAGGVIITLVLIFFVI
GESLPVPIPPASVALMGACLALLLASQSKIDTVHNILRDVDWSTLIFFMSIFVIIGSLEK
TGVTASLAQLLAVVVGQNIAFGAIVLVFTVGLLSSVVPNIPLVVAMVPLLKQYVVNIGFA
GPEILGANFDGQLPAEVLPLFYAMMFGATLGGNGTLVGASSNIVAAGISEQHGRPISFHR
FLRYGLPVMAVQLVVAALFVAWLMFTQQG