Protein Info for SGL_RS16580 in Synechocystis sp000284455 PCC 6803

Annotation: nitrate ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 667 TIGR01184: nitrate ABC transporter, ATP-binding proteins C and D" amino acids 25 to 254 (230 residues), 414.6 bits, see alignment E=5.5e-129 PF00005: ABC_tran" amino acids 25 to 166 (142 residues), 119.5 bits, see alignment E=2.6e-38 PF13379: NMT1_2" amino acids 276 to 525 (250 residues), 276.6 bits, see alignment E=3.7e-86 PF09084: NMT1" amino acids 292 to 514 (223 residues), 28.3 bits, see alignment E=2.4e-10

Best Hits

Swiss-Prot: 100% identical to CMPC_SYNY3: Bicarbonate transport ATP-binding protein CmpC (cmpC) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K11952, bicarbonate transport system ATP-binding protein [EC: 3.6.3.-] (inferred from 100% identity to syn:slr0043)

Predicted SEED Role

"Bicarbonate transporter, bicarbonate binding protein 2" in subsystem CO2 uptake, carboxysome

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (667 amino acids)

>SGL_RS16580 nitrate ABC transporter ATP-binding protein (Synechocystis sp000284455 PCC 6803)
MSLFVAVDNIDKVFSLTDGGEYIALKGINLEIKKGEFVSLIGHSGCGKSTLLNMIAGLDL
PSEGIVTLEGQRIKQPGPDKMVIFQNYSLLPWLTVKQNIALAVDEVMKGASAAERKAIVE
EHINLVGLGHAVDKRPGELSGGMKQRVAIARALAIRPKLLLLDEPFGALDALTRGNLQEQ
LMRICEQYQVTAVMVTHDVDEAVLLSDRIVMLTNGPGSNIGGILEVDIPRPRKRMEVVEH
PSYYSLRSEIIYFLNQQKRIKKLRAKKTTAIARHGLEKVNLELGYVPLVACAPLVVAQEK
GFFAKHGLDEVSLVRETSWRGIVDGIAGGYLDGAQMPAGMPTWLTAGGYREQSIPVVSAL
TMTRNGNAITLSKKLYDQGIYTAEDFRQLLLASDGDRHTLGMVHPSSMHNLLLRYWLAAH
NINPDRDVHLKTIPPAQMVADLKAGTIDGYCVSEPWNLRASMEGAGFSIATDLEIWQNHP
GKVLGVREDWAIAHPNTHVALVKALLEACAYCADPNHEMEIRELLATRQYLSTNIDYIHL
GDPEGRTCRLGNPVEYSHHLFFGDQFNRPSRTEHLWMMTQMARWGDIPFPRNWVEILERV
CRVGVFSTAARELGYDVNYQRQPIALFDGKVFNADDPIAYLNQTVIHRNFTIAEVHLDNP
TPAPVFA