Protein Info for SGL_RS16565 in Synechocystis sp000284455 PCC 6803

Annotation: CmpA/NrtA family ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 452 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF13379: NMT1_2" amino acids 56 to 314 (259 residues), 297.9 bits, see alignment E=4e-93

Best Hits

Swiss-Prot: 100% identical to CMPA_SYNY3: Bicarbonate-binding protein CmpA (cmpA) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K11950, bicarbonate transport system substrate-binding protein (inferred from 100% identity to syn:slr0040)

Predicted SEED Role

"Bicarbonate transporter, bicarbonate binding protein" in subsystem CO2 uptake, carboxysome

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (452 amino acids)

>SGL_RS16565 CmpA/NrtA family ABC transporter substrate-binding protein (Synechocystis sp000284455 PCC 6803)
MGSFNRRKFLLTSAATATGALFLKGCAGNPPDPNAASTGTNPSPQAAGDISPEMMPETAN
IKLGYIPIVEAAPLIIAQEKGFFAKYGMTGVEVSKQANWASARDNVTIGSQGGGIDGGQW
QMPMPHLITEGIITNGNKVPMYVLAQLITQGNGIAVAPMHEGKGVNLDITKAADYIKGFN
KTNGRKFKAAHTFPNVNQDFWIRYWFAAGGVDPDTDIDLLAVPPAETVQGMRNGTMDAFS
TGDPWPYRIVTENIGYMAGLTAQIWPYHPEEYLAIRADWVDKNPKATKALLKGIMEAQQW
IDDPKNRPEVVQIVSGRNYFNVPTTILESPFKGQYTMGDGQPAIDDFQKGPLYWKDGIGN
VSYPYKSHDLWFLTESIRWGFHKNAIPDLDTAQKIIDKVNREDLWREAATEAGFTADIPS
STSRGVETFFDGITFDPANPSAYLQSLAIKKV