Protein Info for SGL_RS15975 in Synechocystis sp000284455 PCC 6803

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 PF00561: Abhydrolase_1" amino acids 26 to 264 (239 residues), 144.4 bits, see alignment E=7.4e-46 PF12146: Hydrolase_4" amino acids 27 to 259 (233 residues), 67.7 bits, see alignment E=1.5e-22 PF12697: Abhydrolase_6" amino acids 27 to 268 (242 residues), 92.4 bits, see alignment E=1.1e-29

Best Hits

Swiss-Prot: 100% identical to PRXC_SYNY3: Putative non-heme chloroperoxidase (slr0314) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K00433, chloride peroxidase [EC: 1.11.1.10] (inferred from 100% identity to syn:slr0314)

Predicted SEED Role

"Similar to non-heme chloroperoxidase" in subsystem Synechocystis experimental

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.10

Use Curated BLAST to search for 1.11.1.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (276 amino acids)

>SGL_RS15975 alpha/beta hydrolase (Synechocystis sp000284455 PCC 6803)
MPYVTVGQENSATIDIYYEDLGAGQPIVLIHGFPLNGDSWEKQVLVLLNAGYRVITYDRR
GFGASSQPSSGYDYDTFAADLHTLMTKLDLQNTVLVGFSMGTGEVTRYLGKYGSERVQKA
VLMAPVPPFLLKTNDNPEGVDQSVFDGIMKAIVDDRPAYFSAFFKEFFNVDVLLGERISN
EAIQASWNVAAGASAKGTLDCVPSWLTDFRDDLPRIDVPTLIIHGDADRILPLESTAARL
PKRIKNSQLEIIPGGPHAINWTHADQVNPLLLNFLQ