Protein Info for SGL_RS15420 in Synechocystis sp000284455 PCC 6803

Annotation: DevA family ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 245 TIGR02982: ABC exporter ATP-binding subunit, DevA family" amino acids 21 to 239 (219 residues), 377.4 bits, see alignment E=1.1e-117 PF00005: ABC_tran" amino acids 42 to 190 (149 residues), 119.7 bits, see alignment E=1.5e-38

Best Hits

Swiss-Prot: 41% identical to LOLD_HAES1: Lipoprotein-releasing system ATP-binding protein LolD (lolD) from Haemophilus somnus (strain 129Pt)

KEGG orthology group: K02003, (no description) (inferred from 100% identity to syn:sll0484)

Predicted SEED Role

"Methionine ABC transporter ATP-binding protein" in subsystem Methionine Biosynthesis or Methionine Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (245 amino acids)

>SGL_RS15420 DevA family ABC transporter ATP-binding protein (Synechocystis sp000284455 PCC 6803)
MAMLLSSPSSDLVTMTPAEPVVAMENLSHFYGTGNLRKQILFDINLRLDEGEVVILKGPS
GSGKTTLLTLMGGLRSAQSGSLRVFGQELNGAKKQDLVQVRRHIGYIFQAHNLLESLTAR
QNVQMAIELHPQYNAQQAKELSIAMLEAVGLGAHINYNPHNLSGGQKQRVAIARALVSHP
KMILADEPTAALDSKSGHDVVELMRKLAREQGSTILIVTHDNRILDVADRIIQLEDGQLC
ADPGE