Protein Info for SGL_RS13970 in Synechocystis sp000284455 PCC 6803

Annotation: pitrilysin family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 428 PF00675: Peptidase_M16" amino acids 28 to 168 (141 residues), 98.8 bits, see alignment E=2.8e-32 PF05193: Peptidase_M16_C" amino acids 175 to 358 (184 residues), 137.4 bits, see alignment E=5.3e-44

Best Hits

KEGG orthology group: K01412, mitochondrial processing peptidase [EC: 3.4.24.64] (inferred from 100% identity to syn:sll0055)

Predicted SEED Role

"Mitochondrial processing peptidase-like protein (EC 3.4.24.64)" in subsystem ZZ gjo need homes (EC 3.4.24.64)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.64

Use Curated BLAST to search for 3.4.24.64

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (428 amino acids)

>SGL_RS13970 pitrilysin family protein (Synechocystis sp000284455 PCC 6803)
MTPSLLPPRLNLPHVEVLPNGLTIIAEQMPVEAISFQLWLRVGSRWEGDEINGTAHFLEH
MVFKGTPRLAMGEFERAIESRGAGTNAATSQDYTQFYFTSAPQDFEHLAPLQLDVVLNPT
IADGPFERERLVVLEEIRRSQDDPQRRIFQQVVQLAFPGTPYARPVLGRREIIENLQAQQ
MRDFHAHWYQPPAMTVTVVGNQSVGNLVETVARSFADCYRVKSPSQTLMPPLVNIPPPFT
KVETTTVVDDSLQQARLILLWRSPGLDQFEKTLPLGVLAVILGRGRVSRLFRELREEKGL
VTAIGASNSTQATQGMFYISAQLPAENIPMVEQYILDHIERLQNEPIPEKDLERIRTQVA
NRFIFGNERPGDRANLYGYYYAQIGDLEPALTYPVQIQALTAADLQKSAQTYLSPTAYGK
VIALPAED