Protein Info for SGL_RS12575 in Synechocystis sp000284455 PCC 6803
Annotation: riboflavin synthase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00793, riboflavin synthase [EC: 2.5.1.9] (inferred from 100% identity to syn:sll0300)Predicted SEED Role
"Riboflavin synthase eubacterial/eukaryotic (EC 2.5.1.9)" (EC 2.5.1.9)
MetaCyc Pathways
- flavin biosynthesis I (bacteria and plants) (8/9 steps found)
- flavin biosynthesis III (fungi) (7/9 steps found)
- flavin biosynthesis II (archaea) (5/10 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.5.1.9
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (226 amino acids)
>SGL_RS12575 riboflavin synthase (Synechocystis sp000284455 PCC 6803) MFTGIIQSLGYLSAQRADRLEISLSPNDAQRVLGDMALGDSIAVDGVCLTVEAIAHQGFF ADVSPETLQRTTLGRAKERRTAVNIETSLRVGGKVGGHFVSGHVDGVGQLLSNEQINNAW LLSFGSVGSLQKQWQEYLAPYLVPKGSIAVNGISLTVADCGEDWFNVAVIPHTYSETNLQ LLQPGDWVNLEGDILGKYAARFLSRGRAMGQTKDIDLAFLAEHGYG