Protein Info for SGL_RS11355 in Synechocystis sp000284455 PCC 6803

Annotation: arsenite efflux transporter Acr3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 383 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 51 to 71 (21 residues), see Phobius details amino acids 91 to 118 (28 residues), see Phobius details amino acids 138 to 160 (23 residues), see Phobius details amino acids 167 to 186 (20 residues), see Phobius details amino acids 198 to 220 (23 residues), see Phobius details amino acids 238 to 260 (23 residues), see Phobius details amino acids 272 to 294 (23 residues), see Phobius details amino acids 306 to 327 (22 residues), see Phobius details amino acids 333 to 354 (22 residues), see Phobius details TIGR00832: arsenical-resistance protein" amino acids 16 to 355 (340 residues), 446.5 bits, see alignment E=3.1e-138 PF01758: SBF" amino acids 61 to 267 (207 residues), 187 bits, see alignment E=1.5e-59

Best Hits

Swiss-Prot: 100% identical to Y944_SYNY3: Uncharacterized transporter slr0944 (slr0944) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K03325, arsenite transporter, ACR3 family (inferred from 100% identity to syn:slr0944)

Predicted SEED Role

"Arsenical-resistance protein ACR3" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (383 amino acids)

>SGL_RS11355 arsenite efflux transporter Acr3 (Synechocystis sp000284455 PCC 6803)
MVNRINPKAIKAGGTLNLFEKYLTLWVALCIVIGIALGKLLPAVAQTLDSWSIYNVSIPI
AICLFFMMYPIMVKIDFSQARQAVKAPKPVILTLVVNWVIKPFTMVIFAQFFLGYLFAPL
LTATEIIRGQEVTLANSYIAGCILLGIAPCTAMVLMWGYLSYSNQGLTLVMVAVNSLAML
FLYAPLGKWLLAASNLTVPWQTIVLSVLIYVGLPLAAGIYSRYWILKHKGRQWFESQFLH
YLSPIAIVALLLTLILLFAFKGELIVNNPLHIFLIAVPLFIQTNFIFLITYVLGLKLKLS
YEDAAPAALIGASNHFEVAIATAVMLFGLNSGAALATVVGVLIEVPVMLMLVEICKKTAF
WFPRDPEKATLLDPRCINQEIRI