Protein Info for SGL_RS10875 in Synechocystis sp000284455 PCC 6803

Annotation: NAD(P)H-hydrate dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 524 TIGR00197: YjeF family N-terminal domain" amino acids 10 to 213 (204 residues), 229.4 bits, see alignment E=3.4e-72 PF03853: YjeF_N" amino acids 32 to 190 (159 residues), 133.3 bits, see alignment E=8.9e-43 TIGR00196: YjeF family C-terminal domain" amino acids 227 to 507 (281 residues), 313.7 bits, see alignment E=1.1e-97 PF01256: Carb_kinase" amino acids 254 to 501 (248 residues), 267.5 bits, see alignment E=1.1e-83

Best Hits

Swiss-Prot: 100% identical to NNR_SYNY3: Bifunctional NAD(P)H-hydrate repair enzyme Nnr (nnr) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: None (inferred from 100% identity to syn:sll1433)

Predicted SEED Role

"NAD(P)HX epimerase / NAD(P)HX dehydratase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (524 amino acids)

>SGL_RS10875 NAD(P)H-hydrate dehydratase (Synechocystis sp000284455 PCC 6803)
MAVTSPWFRAVVSAAQMQEIENWLFTQGMPVAALMEKAALQTAQRLLTLYPLSTYPRIGV
VVGPGHNGGDGLVVARELKLQGYQVQVLQPLDKLKPLTQNHVDYGKSLGIPWVDGVQALA
HCDLIIDALFGVGLTRLITGAIADLITTINNLPIPVVSIDLPSGIETDTGEILGVAVEAD
RSFCLGLWKRAYFQDRALAHLGQTELLGIGLPPQAIANVLGEVWPVQVLGADQAQQTLPL
SRPLVTHKYQQGHLLLICGSQQYAGGALLTTLGARASGVGMVTVAVPMGIKALLHSQCPE
VLVKGLLETPSGAIAGLGNLDLSRYSAVALGPGLGSDVGPLVEEVLSVNCPLILDADGLN
QLAQQQLLPLLAVRTAPTVLTPHGGEFKRLFPDIDQGDRLTAVQTAAAMCQATVLLKGAK
TVIASPTGPTWAIKDSTPALARGGSGDVLTGLMGGILAQPEKFDLAQRVATAAWWHAQAG
ILASQQRTILGVDAQHLAEYLIPACRQWLGPNVANWPANLSHSS