Protein Info for SGL_RS10340 in Synechocystis sp000284455 PCC 6803

Annotation: AGE family epimerase/isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF07221: GlcNAc_2-epim
  • amino acids 36 to 370 (335 residues), 287.7 bits, E=7.3e-90

Best Hits

KEGG orthology group: K01787, N-acylglucosamine 2-epimerase [EC: 5.1.3.8] (inferred from 100% identity to syn:slr1975)

Predicted SEED Role

"N-acylglucosamine 2-epimerase (EC 5.1.3.8)" in subsystem Sialic Acid Metabolism (EC 5.1.3.8)

MetaCyc Pathways

• N-acetylneuraminate and N-acetylmannosamine degradation II (1/3 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.3.8

Protein Sequence (391 amino acids)

>SGL_RS10340 AGE family epimerase/isomerase (Synechocystis sp000284455 PCC 6803)
MIAHRRQELAQQYYQALHQDVLPFWEKYSLDRQGGGYFTCLDRKGQVFDTDKFIWLQNRQ
VWQFAVFYNRLEPKPQWLEIARHGADFLARHGRDQDGNWYFALDQEGKPLRQPYNVFSDC
FAAMAFSQYALASGAQEAKAIALQAYNNVLRRQHNPKGQYEKSYPGTRPLKSLAVPMILA
NLTLEMEWLLPPTTVEEVLAQTVREVMTDFLDPEIGLMREAVTPTGEFVDSFEGRLLNPG
HGIEAMWFMMDIAQRSGDRQLQEQAIAVVLNTLEYAWDEEFGGIFYFLDRQGHPPQQLEW
DQKLWWVHLETLVALAKGHQATGQEKCWQWFERVHDYAWSHFADPEYGEWFGYLNRRGEV
LLNLKGGKWKGCFHVPRALWLCAETLQLPVS