Protein Info for SGL_RS09400 in Synechocystis sp000284455 PCC 6803

Annotation: GTPase HflX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 534 TIGR03156: GTP-binding protein HflX" amino acids 171 to 527 (357 residues), 479.8 bits, see alignment E=2.2e-148 PF13167: GTP-bdg_N" amino acids 190 to 276 (87 residues), 113 bits, see alignment E=1.2e-36 PF16360: GTP-bdg_M" amino acids 278 to 356 (79 residues), 100.6 bits, see alignment E=8.7e-33 PF01926: MMR_HSR1" amino acids 363 to 487 (125 residues), 77.6 bits, see alignment E=1.2e-25

Best Hits

KEGG orthology group: K03665, GTP-binding protein HflX (inferred from 100% identity to syn:slr1521)

Predicted SEED Role

"GTP-binding protein HflX" in subsystem Hfl operon or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (534 amino acids)

>SGL_RS09400 GTPase HflX (Synechocystis sp000284455 PCC 6803)
MELAQRLGAISQEIKQPVSVYVNRRGQIIRVGVGTPRQTQIPPLELPRYGEKRLSGIRCL
TTDLKGEAPRESSLIAMALQRLDALVVLSVTGQGFAKRGGGVTGYIDTGYLAHLLPQSSD
DMGDRVADWVVSPAVALEDLAEEAILDLVESLEAEFEREFIARQVEAGQERVLVMGLKTS
ELDDQSFAEGLTELERLVDSAGAQVLQVMQQNRSKPHPQTVVGEGKVEELALAVQTTGAN
LVVFDRDLSAAQVRNLEQRCGVRVIDRTELILDIFAQRAQSRAGKLQVELAQLEYLLPKL
VGRGQGMSRLGGGIGTRGPGETKLETERRTIQSRIAKLQKQVNELQSHRSRLRNQRQQQA
VPTVAIVGYTNAGKSTLLNALTQADIYAADQLFATLDPTTRRLSLLDPENQTYHPILLTD
TVGFIHKLPDALVDAFRATLEEVTEADLLLQVVDLSDRAWRRQIASVANILAEMPLATAP
MVMVFNKIDQVPSEALAAAQADYPEAIFLAAAQGIGLETLKKRLLEQILTDLTD