Protein Info for SGL_RS08895 in Synechocystis sp000284455 PCC 6803
Annotation: FAD-dependent oxidoreductase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K09879, isorenieratene synthase (inferred from 100% identity to syn:sll0254)MetaCyc: 66% identical to carotenoid chi-ring synthase (Synechococcus sp. PCC 7002)
RXN-10648 [EC: 1.3.99.40]; 1.3.99.40 [EC: 1.3.99.40]; 1.3.99.40 [EC: 1.3.99.40]
Predicted SEED Role
"Phytoene desaturase (EC 1.14.99.-)" in subsystem Carotenoids (EC 1.14.99.-)
MetaCyc Pathways
- synechoxanthin biosynthesis (4/6 steps found)
KEGG Metabolic Maps
- 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation
- Benzoate degradation via hydroxylation
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Carotenoid biosynthesis - General
- Naphthalene and anthracene degradation
- Nicotinate and nicotinamide metabolism
Isozymes
Compare fitness of predicted isozymes for: 1.14.99.-
Use Curated BLAST to search for 1.14.99.- or 1.3.99.40
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (650 amino acids)
>SGL_RS08895 FAD-dependent oxidoreductase (Synechocystis sp000284455 PCC 6803) MTELPPNPNSTVVSRRTALKLLGVGTLGGAIGYSRLAKPQPARYDTDRLDLPQYLSQLKS VVVVGAGLAGLASAYELSKRGFKVTLLEKSPNLGGKVAGWPIQVGEETFQMEHGFHGFFP QYYNLKSIVNELAIADNFRSLDFYSLVFKEGYEPEVFRPSHSAFPWNIVDLTISSPNRLR WGINLTKPAHWQVFRAITGFQIPKSYDQLDSITVSDWVAKGFPKGLYDLYFLPFAKSSLN APDVLSAGELMQFFHFYFFGNPEGLAFNGTKDDMVTSLVMPMVESIKAHGGQIITEATVS AINCDQGLIQSLQYVQGDDPVSDVPFTVPRNDLLTQANPGGNVYYGAGDRVYWAKPEGKE ALSLTCSHQGCTVAKQENGQFICPCHGAVYDADGQVIQGPAKRNLAKFAVKPGSSATEVQ LVSRTKDKPPAQTLKADYYVLAADVVGMKNLADRLGGDVNPQFVQQVKNLAVADPFAVAR FWFDQDFEWPHSNFASLSGYRLTDSITLYHRIQNQFIAWAERTGGSVVELHAYCYKEKEF PTQGDLLATFEQELYEIVPSLATAKLLHRELVNQKNFSGFPPNSYGDRPETETPVANLLF AGDWVKMPFPCGLMERAISSGLLSANAICHQEGLQRRELLTVMPEGILQI