Protein Info for SGL_RS08315 in Synechocystis sp000284455 PCC 6803

Annotation: DNA mismatch repair protein MutS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 878 TIGR01070: DNA mismatch repair protein MutS" amino acids 25 to 866 (842 residues), 937.4 bits, see alignment E=4.4e-286 PF01624: MutS_I" amino acids 26 to 141 (116 residues), 136.6 bits, see alignment E=1.1e-43 PF05188: MutS_II" amino acids 150 to 287 (138 residues), 112.9 bits, see alignment E=3.7e-36 PF05192: MutS_III" amino acids 305 to 596 (292 residues), 184.1 bits, see alignment E=9.8e-58 PF05190: MutS_IV" amino acids 465 to 555 (91 residues), 104.7 bits, see alignment E=6.4e-34 PF00488: MutS_V" amino acids 652 to 839 (188 residues), 280.6 bits, see alignment E=1.7e-87

Best Hits

Swiss-Prot: 100% identical to MUTS_SYNY3: DNA mismatch repair protein MutS (mutS) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K03555, DNA mismatch repair protein MutS (inferred from 100% identity to syn:sll1165)

Predicted SEED Role

"DNA mismatch repair protein MutS" in subsystem DNA repair, bacterial MutL-MutS system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (878 amino acids)

>SGL_RS08315 DNA mismatch repair protein MutS (Synechocystis sp000284455 PCC 6803)
MTDTPILGTVKEPQRDYRTLDRQKLTPMFQHYTEVKEQYQGALLLYRVGDFFECFFQDAV
IIARELELILTSKEGGKEIGRVAMTGVPHHALDRYARQLVEKGYAVAICDQVEDAAEAQA
EKRMVERQVTKLLTPGTLTDDSMLPAKRNNFLAAIAMVEDKWGLAHADISTGEFFTCQSS
NLDDLAVELLRLQPSEVLIPTSAPDIRNILRPGEPSEHIPKQLPTSFCYSLRSQAPFSLV
EAKQRLLTTFRVKSLEGMGCEGLPLAIRAAGGLLEYIEDTQKAHVVPIQPLKTYGLTDFL
VLDHQTRRNLEINQTVRDGSFHGSLLWALDRTSTTMGSRALRRWLLQPLLDLKGIQARQD
TIQELYHHPALRQDLRQLLRQIYDLERLTGRIGANTASARDVYGLASSLVRLTDLAELAQ
EGHSPYLKALQTVPPELEELGKYVLAHIVENPPLHIREGNLIRSGVNPTLDEMRQSLEDD
NQWLANLEVTEREKTGIANLKVGYNKAFGYYLSLPRSKSEQAPDNYIRKQTLVNEERYIT
PELKERETRILTAQADLNQLEYEIFTEVRATVAEKAQPIRDVAKAVAAIDVLAGLAEVAV
YQGYCRPIMQMEPGLIDIEAGRHPVVEQSLGAGFFVANDTQLGHDHWHPDLVILTGPNAS
GKSCYLRQVGLIQLMAQTGSFIPAKTATLSICDRIFTRVGAVDDLATGQSTFMVEMNETA
NILNHATAKSLVLLDEIGRGTATFDGLAIAWSVAEYLAGEIQARTIFATHYHELNELASL
LENVANFQVTVKELPEEIIFLHQVTPGGADKSYGIEAGRLAGLPSSVITRARQVMAQIEK
HSKIAVGLRKGNRGKVMASQAAAEAAEDQAKQLDIFGF