Protein Info for SGL_RS07730 in Synechocystis sp000284455 PCC 6803

Annotation: DNA/RNA nuclease SfsA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 TIGR00230: sugar fermentation stimulation protein" amino acids 1 to 237 (237 residues), 358.4 bits, see alignment E=7.5e-112 PF17746: SfsA_N" amino acids 16 to 82 (67 residues), 90.6 bits, see alignment E=5.4e-30 PF03749: SfsA" amino acids 86 to 225 (140 residues), 149.5 bits, see alignment E=5.3e-48

Best Hits

Swiss-Prot: 100% identical to SFSA_SYNY3: Sugar fermentation stimulation protein homolog (sfsA) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K06206, sugar fermentation stimulation protein A (inferred from 100% identity to syn:sll2014)

Predicted SEED Role

"Sugar/maltose fermentation stimulation protein homolog" in subsystem Fermentations: Mixed acid

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (237 amino acids)

>SGL_RS07730 DNA/RNA nuclease SfsA (Synechocystis sp000284455 PCC 6803)
MDFLYPYPPLISGILVKRYKRFLADVELDNGEIVTAHCPNTGPMTGVCQVGAQVYLSKSD
NPQRKLAYTWEMIQIDGTWVGVNTALPNRVIKQALADRIFPNLTNSYDTFKPEVPYGKDK
KSRIDFLLTKPEEKSIYVEVKNTTLSQEKLALFPDTETTRGQKHLQELIDILPTARAVML
YFINRGDCTHFSPGDAYDRRYGELFRQAIAAGVEVMPCRFMVNPEGVKFLGMAELVV