Protein Info for SGL_RS05960 in Synechocystis sp000284455 PCC 6803

Annotation: chromosome segregation protein SMC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 PF02463: SMC_N" amino acids 3 to 680 (678 residues), 116.1 bits, see alignment E=5e-37 amino acids 885 to 1192 (308 residues), 108.1 bits, see alignment E=1.4e-34 TIGR02168: chromosome segregation protein SMC" amino acids 3 to 1189 (1187 residues), 579.8 bits, see alignment E=1.2e-177 TIGR02169: chromosome segregation protein SMC" amino acids 3 to 1200 (1198 residues), 1150 bits, see alignment E=0 PF13175: AAA_15" amino acids 4 to 423 (420 residues), 40.4 bits, see alignment E=9.1e-14 PF13555: AAA_29" amino acids 5 to 49 (45 residues), 27.2 bits, see alignment (E = 8.1e-10) PF13476: AAA_23" amino acids 6 to 295 (290 residues), 62.3 bits, see alignment E=3.1e-20 PF13304: AAA_21" amino acids 27 to 72 (46 residues), 27.8 bits, see alignment (E = 8e-10) PF06470: SMC_hinge" amino acids 542 to 656 (115 residues), 93.1 bits, see alignment E=4.9e-30

Best Hits

Swiss-Prot: 100% identical to SMC_SYNY3: Chromosome partition protein Smc (smc) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K03529, chromosome segregation protein (inferred from 59% identity to cyp:PCC8801_1464)

Predicted SEED Role

"Chromosome partition protein smc" in subsystem Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1200 amino acids)

>SGL_RS05960 chromosome segregation protein SMC (Synechocystis sp000284455 PCC 6803)
MVYVKRIELSHFKSFGGTTAIPFLPGFTVVSGPNGSGKSNILDALLFCLGLATSKGMRAE
RLPDLVNNTFKGNRGSSEASVSVTFELHDGENLSEPGANHNGNGNGAKISKEWTVTRRLK
VTKGGNYSSNYYINGETATVTELHEQLNELRIYPEGYNIVLQGDVTRIITMNSKERREII
DELAGVAEFDRKIVKTKETLTEVQDREERCQIIATELERTLERLAADRQKAEKYQALRQQ
VQEKQGWAKVIQYKAVEQQRQKLWGQLERDREQSQQIQQALDQRSQAIQTQQTELEKLNA
QVKALGEEEQLAVAAQLATQKAQRDQLQQRYNDGDRQITNHQQQVGQIQAEISQSQQQFL
HIQQEKSFHNTQTLPQLEAAVQTSQQQLEQLRHQAQAIASASEAWVQEQTQLSRTVNQLQ
DELIPQRSQLAQLEERQQQLLTNLAELTPLLTKVSVELEEKQFAQGQFNFQGEALTSQIQ
TLASDLAQLEQERSLLQETQTRLLKEQQEKQRQLDKLEAASQAQQEVQGTYATKVILQSD
LPGVCGLVAQLGQVEPQYQLALEIAAGGRLGFLVVEDDGVAAAGIEILKQAKAGRATFLP
LNKIRPPKGQNPNLSYAHGYIDLAVNLIDGDRRYADIFAFIFGNTIVFDTLVNARNHLGK
HRIVTLEGDLLEASGAMSGGSRNQRSGLRFGTMVSEDTAEVKQLRQRLQDIQQVQGRNEE
LLLERTVRSRQLTQQLMEMRQQQREAQLHGEQTERDIARLSQQQTQINQQQINQQQKLAE
LQQNLALLQQSLPPLEQQLASAQQQLTALETSQTHQQWQTIQIQIRTVEAEYQRQLQALR
QGEDHLKDLQNSSQRLEEKIAQAQEKIAQHQAQDLTLAQEQEQLKIALAEMNGAIQTTEA
QLAKLSEKLGSTKQERDRLETQLNQLRSQQQEQQWQWEKLQTNQQEYQENLTQLQTQLEA
LEQDLPDPWPEIPLLQDRDEANLDFANILEELERSIRNGQKRLEAMEPVNMLALQEYEKT
EARLGELSEKLQTIAGERTELLLRIENFTTLRRRSFQDAFDAVNKNFQIIFAELSDGDGY
LQLDDAEDPFNGGLNLVAHPKGKPVRRLSSMSGGEKSLTALSFIFALQRYRPSPFYGFDE
VDMFLDGANVEKLSKMVRKQAQQAQFIVVSLRRPMIEAAERTIGVTQARGAHTQVLGIKL