Protein Info for SGL_RS04685 in Synechocystis sp000284455 PCC 6803

Annotation: molecular chaperone DnaK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 771 TIGR02350: chaperone protein DnaK" amino acids 3 to 600 (598 residues), 898 bits, see alignment E=1.3e-274 PF00012: HSP70" amino acids 4 to 599 (596 residues), 804 bits, see alignment E=7.2e-246 PF06723: MreB_Mbl" amino acids 114 to 372 (259 residues), 51.2 bits, see alignment E=9e-18

Best Hits

Swiss-Prot: 100% identical to DNAK3_SYNY3: Chaperone protein dnaK3 (dnaK3) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K04043, molecular chaperone DnaK (inferred from 100% identity to syn:sll1932)

Predicted SEED Role

"Chaperone protein DnaK" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (771 amino acids)

>SGL_RS04685 molecular chaperone DnaK (Synechocystis sp000284455 PCC 6803)
MGKVVGIDLGTTNSVVAVMEGGKPIVIANAEGMRTTPSVVGFNKEGELVVGQMGRRQAVL
NPQNTFYGVKRFMGRRYTDLTPESKRVAYTIRRDDRDNIKVRCPRLKKDFAPEEISAMIL
RKLAEEASRYLGEKVTGAVITVPAYFNDSQRQATRDAGKIAGLEVLRIINEPTAASLAYG
LDQGRIQKILVFDLGGGTFDVSVLEVGDGIFEVKATSGDTQLGGNDFDRRIVDWLAEKFL
EAEKVDLRQDRQALQRLTEAAEKAKIELSGVGTTEINLPFITATEDGPKHLETQLSRSEF
EDLCGDLVTRLQRPVKRVLKDAGLSPVQIDEVVLVGGGTRMPMVKGLVRSFIDREPNENV
NPDEVVAIGAAIQAGILDGEVKDILLLDVTPLSFGLETIGGVMKKLLPRNTTIPVRKSDI
FSTGENNQTVVEVHVLQGEREMASDNISLGRFKLSGIPPAPRGVPQVQVSFDIDANGILQ
VTARDKTTGREQSITVQGASILSEGEVNRMIQEAETFAAQDRERRERIEKRNSAKALTDQ
AQRRLKEVTLDFGSAFTVSYRRQVDALCSEILDSLEKDDERRLDRAQADLQDVLYELNRE
VRLQYDDKEEGFFEAIKKTFTGDFDDDDDYYNRRPAPRDDYRGGNDYGRYDDYNYNAPSR
REAPMPRAGAGRGPSLSKDYRSTAYADWDQSRVTRQRPYQGESLGGTYDDRRSSPQDDYS
RGDRQKDYDYRENAPSRSGRGGNGRYGERPAQPGRNAPLQNGWDDDDDDWF