Protein Info for SGL_RS04175 in Synechocystis sp000284455 PCC 6803

Annotation: PQQ-dependent sugar dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 412 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF07995: GSDH" amino acids 65 to 409 (345 residues), 431.4 bits, see alignment E=1.3e-133

Best Hits

Swiss-Prot: 100% identical to Y1608_SYNY3: Uncharacterized protein slr1608 (slr1608) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: None (inferred from 100% identity to syn:slr1608)

Predicted SEED Role

"PQQ-dependent oxidoreductase, gdhB family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (412 amino acids)

>SGL_RS04175 PQQ-dependent sugar dehydrogenase (Synechocystis sp000284455 PCC 6803)
MLIPFLFKLTLPLASGIALSSCGTLPEADLGTAAGNQTSSEPTNSVEIVQANQPEIKAVP
VIDGLEHPWGMAWLPNGDILITERPGRLRIVRDGVLDPEAIAGVVAVSTVSAQQLFASQQ
GGLLDIALHPRFAENRFVYFTYSHGTQQANRTRVARAVFDGEKLTDWQVIFEVGQTKPGG
QHFGSRLTWLPDETLLVSIGDGGNPPVELEGDFIRQQAQNRASHLGKIIRINDDGTVPAD
NPFRNDPKAAPEVWSYGHRNIQGLAYDPVTQKVWATEHGSRGGDELNLIQKGKNYGWPVV
SFSKEYSTDQPVAPATSRPDMVDPLQIWTPAIAPSGLTIYNGDRHPEWQGTIFAGGLVDR
GIRHLRLDENNQIIDETTISIGQRVRDVRQGPDGHVYVLTDQNNGQLLRLES