Protein Info for SGL_RS02865 in Synechocystis sp000284455 PCC 6803

Annotation: serine/threonine phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 668 PF12773: DZR" amino acids 4 to 48 (45 residues), 32.4 bits, see alignment 1.3e-11 PF00481: PP2C" amino acids 432 to 549 (118 residues), 36 bits, see alignment E=9.7e-13 PF13672: PP2C_2" amino acids 438 to 631 (194 residues), 50.3 bits, see alignment E=3.4e-17

Best Hits

KEGG orthology group: K01090, protein phosphatase [EC: 3.1.3.16] (inferred from 100% identity to syn:sll1033)

Predicted SEED Role

"Protein phosphatase 2C (EC 3.1.3.16)" (EC 3.1.3.16)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.16

Use Curated BLAST to search for 3.1.3.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (668 amino acids)

>SGL_RS02865 serine/threonine phosphatase (Synechocystis sp000284455 PCC 6803)
MLICLQCSAENPNRNTDCQKCGASLKEHPCNQCGEMVQYGEAHCPHCGAIAGQILTVLVT
VPVAVGPDGKPEQSFDPQGIRLYENFIDVGQRYQLLTPVEENPFVVDEVGEGEQIVLKSR
VVDCQPLQPSVLKVLLSQQGDLLTRLPQMSDGEIMANDTWSSLNLPKAIIPYFRFPVLMP
KIPEVYDAWCDGDYGFVLMEDRSEWDVLADVLRDEGDSLPGLEMVFWINQLFQLWQQLSS
AGCGKGLLMGQNLLVDEDQNIALEQIYANGGTPVSLEEFGSLLHGYFSPVPSAGEDLLAI
LQRAAQGEYQDVDDLFADIEDLVITVEEEGENFIIHEVDFEQIPDDVFAAIESGESAFKS
EEVAPSINPVTMPDVNVFDSEEVDDVPTAVLPMQLISLVDAGYTDRGGHRQHNEDFFGIT
TSVETHRNNHGKTIKAQGVYVVCDGMGGHAAGEVASQMGVKTLLEYFQIVMANRLPDKNT
ITEGINLANQKIYEVNQSNASSGSGRMGTTLVMMLVKDTTMAIAHVGDSRIYRVTRKNGL
EQLTVDHEVGQQAILNGLDPTLAYARPDAYQLTQALGPHSSSYLQPDVAIFEIEEDCLIL
LCSDGISDNDFVEEHWQELLLPYVSSSQDVDRGLRKLMEAANEYNGHDNLTGVLVRLKVR
PQIPLDVW