Protein Info for SGL_RS02280 in Synechocystis sp000284455 PCC 6803

Annotation: Rne/Rng family ribonuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 674 TIGR00757: ribonuclease, Rne/Rng family" amino acids 13 to 410 (398 residues), 510.3 bits, see alignment E=2.1e-157 PF10150: RNase_E_G" amino acids 113 to 385 (273 residues), 318.7 bits, see alignment E=1.6e-99

Best Hits

Swiss-Prot: 100% identical to RNE_SYNY3: Ribonuclease E/G-like protein (rne) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K08300, ribonuclease E [EC: 3.1.26.12] (inferred from 100% identity to syn:slr1129)

Predicted SEED Role

"Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-)" in subsystem Bacterial Cell Division or RNA processing and degradation, bacterial (EC 3.1.4.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.26.12 or 3.1.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (674 amino acids)

>SGL_RS02280 Rne/Rng family ribonuclease (Synechocystis sp000284455 PCC 6803)
MPKQIVIAEKHQVAAVFWKDQIQELVVSTGSQQVGDIYLGLVDNILPSIDAAFINIGDTE
KNGFIHVSDLGPVRLRRTAGSISELLSPQQRVLVQVMKEPTGNKGPRLTGNISMPGRYMV
LMPYGRGVNLSRRINREEERSRLRALAVLIKPPGMGLLVRTEAEDVPEDAIIEDLENLQK
QWELVQQQAMTRSAPMLLDRDDDFIKRVLRDMYSSEVNRIVVDTPAGMKRIKQQLMNWDQ
GRLPEGVLIDCHRESLSILEYFRVNATIREALKPRVDLPSGGYIIIEPTEALTVIDVNSG
SFTHSANSRETVLWTNYEAATEIARQLKLRNIGGVIIIDFIDMDSHKDQLQLLEHFNRCL
ETDKARPQIAQLTELGLVELTRKRQGQNLYELFGQPCPECGGLGHLVELPGEKGFVSLSP
TAVNSSIPPRLVEKPILSPPVAKVNDLPKKEEAKISSPLDLLFHPNYQEQGDRDSNRRRR
RRRGSEFSEKENIKSVGISRSKGPSPSPTKEKVTGTAPPRRERPSRRVEKTLVPVDVAMT
TLEQDIYARMGISPLIKTEYADQDPRSFMVSVVTAGAALEGNTNGSGSLVNAVITTVDNG
DNGDNVPSDGLTIVSEVTAPTPVIEQPREETVEPEQVVLPQLDDETPAAPVAEESAPIET
KKRPGRRRRRSSAE