Protein Info for Rv3824c in Mycobacterium tuberculosis H37Rv

Annotation: Conserved polyketide synthase associated protein PapA1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 511 PF00668: Condensation" amino acids 71 to 385 (315 residues), 55.4 bits, see alignment E=2.4e-19

Best Hits

Swiss-Prot: 100% identical to PAPA1_MYCBO: Acyltransferase papA1 (papA1) from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)

KEGG orthology group: None (inferred from 100% identity to mtf:TBFG_13858)

MetaCyc: 100% identical to 2'-n-acyl-2-O-sulfo-trehalose (hydroxy)phthioceranyltransferase (Mycobacterium tuberculosis H37Rv)
RXN-17319 [EC: 2.3.1.283]; 2.3.1.283 [EC: 2.3.1.283]

Predicted SEED Role

"Polyketide synthase associated protein PapA1"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.283

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (511 amino acids)

>Rv3824c Conserved polyketide synthase associated protein PapA1 (Mycobacterium tuberculosis H37Rv)
VRIGPVELSAVKDWDPAPGVLVSWHPTPASCAKALAAPVSAVPPSYVQARQIRSFSEQAA
RGLDHSRLLIASVEVFGHCDLRAMTYVINAHLRRHDTYRSWFELRDTDHIVRHSIADPAD
IEFVPTTHGEMTSADLRQHIVATPDSLHWDCFSFGVIQRADSFTFYASIDHLHADGQFVG
VGLMEFQSMYTALIMGEPPIGLSEAGSYVDFCVRQHEYTSALTVDSPEVRAWIDFAEINN
GTFPEFPLPLGDPSVRCGGDLLSMMLMDEQQTQRFESACMAANARFIGGMLACIAIAIHE
LTGADTYFGITPKDIRTPADLMTQGWFTGQIPVTVPVAGLSFNEIARIAQTSFDTGADLA
KVPFERVVELSPSLRRPQPLFSLVNFFDAQVGPLSAVTKLFEGLNVGTYSDGRVTYPLST
MVGRFDETAASVLFPDNPVARESVTAYLRAIRSVCMRIANGGTAERVGNVVALSPGRRNN
IERMTWRSCRAGDFIDICNLKVANVTVDREA