Protein Info for Rv3689 in Mycobacterium tuberculosis H37Rv

Annotation: Probable conserved transmembrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 451 transmembrane" amino acids 155 to 177 (23 residues), see Phobius details amino acids 203 to 226 (24 residues), see Phobius details amino acids 247 to 276 (30 residues), see Phobius details amino acids 287 to 315 (29 residues), see Phobius details amino acids 335 to 362 (28 residues), see Phobius details amino acids 383 to 410 (28 residues), see Phobius details

Best Hits

KEGG orthology group: None (inferred from 100% identity to mbo:Mb3714)

Predicted SEED Role

"FIG00761799: membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (451 amino acids)

>Rv3689 Probable conserved transmembrane protein (Mycobacterium tuberculosis H37Rv)
LHKRYAPQRPKPDTETYIEKCTDRRQDGGHDERRQLLRPVSMLPPGYPVEPPPVAPGYAP
AGYPPYPATPPGYGPPGYGAPPSYGPPPGYGPPLGYPAAPPGCGPPPGYGPPLGYGPPVA
PGAVKPGIIPLRPLTLSDIFNGAVGYIRANPKATLGLTAMVVVTLQIISLVALFGPMTAF
GDIVTGEPDELTGAVVGGWSASFGASLLVSWLAGVLLSGMLTVIVGRAVFGSPITVGEAW
AKVRGRLLALFGLALLEAAGVVAVLGLAVVILSGVAAAANEAAAALLGFPLLLVVGVSLA
YLYVVLLFAPVLIVLERLPIVEAITRSFALVRHGFWRVLGIRLLTVLVVGVVGNAIAAPF
MIVGEIVTAVTASDGSVTMRLVGATLSAIGVTIGQIVTAPFSAGVVVLLYTDRRIRAEAF
DLVLQTGLEAGPAGGPAPVESTDNLWLTRPF