Protein Info for Rv3481c in Mycobacterium tuberculosis H37Rv

Annotation: Probable integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 229 transmembrane" amino acids 14 to 39 (26 residues), see Phobius details amino acids 49 to 73 (25 residues), see Phobius details amino acids 85 to 104 (20 residues), see Phobius details amino acids 125 to 152 (28 residues), see Phobius details amino acids 163 to 186 (24 residues), see Phobius details amino acids 207 to 226 (20 residues), see Phobius details PF11139: SfLAP" amino acids 18 to 227 (210 residues), 223.5 bits, see alignment E=1.1e-70

Best Hits

KEGG orthology group: None (inferred from 100% identity to mtf:TBFG_13516)

Predicted SEED Role

"PROBABLE INTEGRAL MEMBRANE PROTEIN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (229 amino acids)

>Rv3481c Probable integral membrane protein (Mycobacterium tuberculosis H37Rv)
MRGLLPVAGHWVSVLTGLVPLALVIALSPLSVIPAVLVVHSPQPRPSSLAFLGGWLLGLA
VVTAVFVAASGALGGLSTTSPAWASWLRVVLGSALIVFGVLRWLTRHRHTEMPGWMRAFA
SFTPARAGLVGAVLVVVRPEVLIICAAAGLAIGSGGHGAAGSWIYTAFFAMLAASTVAIP
ILAYVAAGDRLDDSLERLKDWMEKNHAGMVAAILVVIGLLLLYNGVHAM