Protein Info for Rv3427c in Mycobacterium tuberculosis H37Rv

Annotation: Possible transposase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 251 PF01695: IstB_IS21" amino acids 12 to 245 (234 residues), 172.7 bits, see alignment E=2e-54 PF00308: Bac_DnaA" amino acids 72 to 208 (137 residues), 31.1 bits, see alignment E=4.4e-11 PF00004: AAA" amino acids 104 to 204 (101 residues), 21.7 bits, see alignment E=4.7e-08

Best Hits

Swiss-Prot: 100% identical to Y3427_MYCTU: Putative ATP-binding protein Rv3427c in insertion sequence (Rv3427c) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

KEGG orthology group: None (inferred from 100% identity to mra:MRA_3467)

Predicted SEED Role

"Mobile element protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (251 amino acids)

>Rv3427c Possible transposase (Mycobacterium tuberculosis H37Rv)
MSICDPALRNALRTLKLSGMLDTLDARLAQTRNGDLGHLEFLQALREDEIARRESAALTR
RLRRAKFEAQATFEDFDFTANPKLPGAMLRDLAALRWLDAGESVILHGPVGVGKTHVAQA
LVHAVARRGGDVRFAKTSRMLSDLAGGHADRSWGQRIREYTKPLVLILDDFAMREHTAMH
ADDLYELISDRAITGKPLILTSNRAPNNWYGLFPNPVVAESLLDRLINTSHQILMDGPSY
RPRKRPGRTTS