Protein Info for Rv3361c in Mycobacterium tuberculosis H37Rv

Annotation: Conserved protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 183 PF13576: Pentapeptide_3" amino acids 29 to 69 (41 residues), 30.6 bits, see alignment 4.8e-11 PF00805: Pentapeptide" amino acids 32 to 69 (38 residues), 20.2 bits, see alignment 5.2e-08 amino acids 88 to 126 (39 residues), 30.8 bits, see alignment 2.5e-11 amino acids 122 to 148 (27 residues), 24.3 bits, see alignment 2.8e-09 PF13599: Pentapeptide_4" amino acids 48 to 121 (74 residues), 41.3 bits, see alignment E=2.3e-14

Best Hits

Swiss-Prot: 100% identical to MFPA_MYCTU: Pentapeptide repeat protein MfpA (mfpA) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

KEGG orthology group: None (inferred from 100% identity to mra:MRA_3401)

Predicted SEED Role

"pentapeptide repeat family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (183 amino acids)

>Rv3361c Conserved protein (Mycobacterium tuberculosis H37Rv)
LQQWVDCEFTGRDFRDEDLSRLHTERAMFSECDFSGVNLAESQHRGSAFRNCTFERTTLW
HSTFAQCSMLGSVFVACRLRPLTLDDVDFTLAVLGGNDLRGLNLTGCRLRETSLVDTDLR
KCVLRGADLSGARTTGARLDDADLRGATVDPVLWRTASLVGARVDVDQAVAFAAAHGLCL
AGG