Protein Info for Rv3331 in Mycobacterium tuberculosis H37Rv

Annotation: Probable sugar-transport integral membrane protein SugI

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 502 transmembrane" amino acids 52 to 77 (26 residues), see Phobius details amino acids 92 to 114 (23 residues), see Phobius details amino acids 121 to 140 (20 residues), see Phobius details amino acids 146 to 167 (22 residues), see Phobius details amino acids 179 to 200 (22 residues), see Phobius details amino acids 206 to 225 (20 residues), see Phobius details amino acids 286 to 307 (22 residues), see Phobius details amino acids 319 to 345 (27 residues), see Phobius details amino acids 352 to 373 (22 residues), see Phobius details amino acids 384 to 408 (25 residues), see Phobius details amino acids 421 to 443 (23 residues), see Phobius details amino acids 449 to 469 (21 residues), see Phobius details TIGR00879: MFS transporter, sugar porter (SP) family" amino acids 50 to 481 (432 residues), 297.4 bits, see alignment E=8.9e-93 PF00083: Sugar_tr" amino acids 56 to 485 (430 residues), 303.3 bits, see alignment E=3.2e-94 PF07690: MFS_1" amino acids 60 to 422 (363 residues), 115.6 bits, see alignment E=2.5e-37

Best Hits

KEGG orthology group: None (inferred from 99% identity to mtf:TBFG_13363)

Predicted SEED Role

"PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN SUGI"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (502 amino acids)

>Rv3331 Probable sugar-transport integral membrane protein SugI (Mycobacterium tuberculosis H37Rv)
VTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRSGRRALLVGLTAAS
VGVLYGYDLSAIAGALLSLSEEFELTTREQELLTTTAVLGQIAGALGGGILANAIGRKKS
VVLIVAGYAVFALLGATSVSVPMLVVARLLLGVTIGLSVVVVPVYVAESAPAAVRGSLVT
AYQLATLSGIVVGYLVGYLLAGSHGWRAMFGLAAAPATLLLPLLWRMPDTARWYLLKGRI
ADARSALRRIQPEADIDAELADMAAAVDERGGGIGEMVRRPYLRATLFVIALGFLVQITG
INAIIYYSPRLFAAMGFAGYFAMLALPAMVQVAGLAAVCASLFLVDRLGRRPILLSGIAT
MITADAVLITVFANDSDGGTGLVLGFAGVLLFIIGFNFGFGSLVWVYAAESFPSRLRSMG
SSPMLTSTLTANAIVAAFSLTMLRVLGGAGVFAVFGTFAVVAFVVVYRFAPETKGRKLEE
IRHFWENGGRWPAERSPAADEP