Protein Info for Rv3292 in Mycobacterium tuberculosis H37Rv

Annotation: Conserved hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 415 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF21723: DUF1338_N" amino acids 11 to 191 (181 residues), 170.9 bits, see alignment E=2.4e-54 PF07063: DUF1338" amino acids 196 to 371 (176 residues), 196.9 bits, see alignment E=2.9e-62

Best Hits

Swiss-Prot: 100% identical to Y3292_MYCTU: Uncharacterized protein Rv3292 (Rv3292) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

KEGG orthology group: None (inferred from 100% identity to mtu:Rv3292)

Predicted SEED Role

"Uncharacterized protein Rv3292/MT3391"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (415 amino acids)

>Rv3292 Conserved hypothetical protein (Mycobacterium tuberculosis H37Rv)
MSRSKRLQTGQLRARFAAGLSAMYAAEVPAYGTLVEVCAQVNSDYLTRHRRAERLGSLQR
VTAERHGAIRVGNPAELAAVADLFAAFGMLPVGYYDLRTAESPIPVVSTAFRPIDANELA
HNPFRVFTSMLAIEDRRYFDADLRTRVQTFLARRQLFDPALLAQARAIAADGGCDADDAP
AFVAAAVAAFALSREPVEKSWYDELSRVSAVAADIAGVGSTHINHLTPRVLDIDDLYRRM
TERGITMIDTIQGPPRTDGPDVLLRQTSFRALAEPRMFRDEDGTVTPGILRVRFGEVEAR
GVALTPRGRERYEAAMAAADPAAVWATHFPSTDAEMAAQGLAYYRGGDPSAPIVYEDFLP
ASAAGIFRSNLDRDSQTGDGPDDAGYNVDWLAGAIGRHIHDPYALYDALAQEERR