Protein Info for Rv3267 in Mycobacterium tuberculosis H37Rv

Annotation: Conserved protein (CPSA-related protein)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 498 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF03816: LytR_cpsA_psr" amino acids 95 to 263 (169 residues), 145.9 bits, see alignment E=1.1e-46 TIGR00350: cell envelope-related function transcriptional attenuator common domain" amino acids 95 to 264 (170 residues), 116.7 bits, see alignment E=5.7e-38 PF13399: LytR_C" amino acids 365 to 449 (85 residues), 54.1 bits, see alignment E=2.5e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to mtf:TBFG_13296)

Predicted SEED Role

"Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily A1 (as in PMID19099556)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (498 amino acids)

>Rv3267 Conserved protein (CPSA-related protein) (Mycobacterium tuberculosis H37Rv)
VMSAQRVVRTVRTARAISTALAVAIVLGTGVAWSSVRSFEDGIFHMSAPSLGHGGDDGAI
DILLVGLDSRTDAHGNPLSAEELATLHAGDEEATNTDTIILIRVPNNGKSATAISIPRDS
YVAAPGLGKTKINGVYGQTRETKRAGLVQAGASPTEAAAAGTEAGREALIKTVADLTGVT
VDHYAEIGLLGFALIADALGGVDVCLKEPVYEPLSGADFPAGRQKLNGPQALSFVRQRHD
LPRGDLDRVVRQQAVMAALAHRVISGQTLSSPATLKRLEQAVQRSVVLSSGWDIMDFVRQ
LQKLAGGNVAFATIPVLDGAGWSDDGMQSVVRVDPRQVQDWVVGLLHEQDQGKTDELAYT
PAKTTANVVNDTDINGLAAAVSKVLSSKGFTTGSVGNNDGDHVPGSQVRAAKADDLGAQQ
VAKELGGLPVVADASIAPGSVRVVLANDYSGPGSGLGGSDPNGVVSPARAFNLGSADDTT
PPPSPILTAGSDAPECIN