Protein Info for Rv3213c in Mycobacterium tuberculosis H37Rv

Annotation: Possible SOJ/para-related protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 266 PF10609: ParA" amino acids 5 to 247 (243 residues), 32.9 bits, see alignment E=1.7e-11 PF13614: AAA_31" amino acids 5 to 178 (174 residues), 186 bits, see alignment E=2.2e-58 PF06564: CBP_BcsQ" amino acids 6 to 160 (155 residues), 45.9 bits, see alignment E=1.8e-15 PF01656: CbiA" amino acids 7 to 230 (224 residues), 92.2 bits, see alignment E=9e-30 PF00142: Fer4_NifH" amino acids 12 to 260 (249 residues), 31.4 bits, see alignment E=4.8e-11 PF02374: ArsA_ATPase" amino acids 12 to 135 (124 residues), 35.8 bits, see alignment E=1.9e-12

Best Hits

Swiss-Prot: 42% identical to SOJ_BACSU: Sporulation initiation inhibitor protein Soj (soj) from Bacillus subtilis (strain 168)

KEGG orthology group: K03496, chromosome partitioning protein (inferred from 100% identity to mtb:TBMG_03258)

Predicted SEED Role

"Chromosome (plasmid) partitioning protein ParA" in subsystem Bacterial Cytoskeleton or Plasmid replication or Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (266 amino acids)

>Rv3213c Possible SOJ/para-related protein (Mycobacterium tuberculosis H37Rv)
MTDTRVLAVANQKGGVAKTTTVASLGAAMVEKGRRVLLVDLDPQGCLTFSLGQDPDKLPV
SVHEVLLGEVEPNAVLVTTMEGMTLLPANIDLAGAEAMLLMRAGREYALKRALAKFSDRF
DVVIIDCPPSLGVLTLNGLTAADKAIVPLQCEMLAHRGVGQFLRTVADVQQITNPNLRLL
GALPTLYDSRTTHTRDVLLDVADRYDLQVLAPPIPRTVRFAEASASGSSVMAGRKNKGAV
AYRELAQALLKHWKTGRPLPTFTVDL