Protein Info for Rv3093c in Mycobacterium tuberculosis H37Rv

Annotation: Hypothetical oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 TIGR03841: probable F420-dependent oxidoreductase, Rv3093c family" amino acids 8 to 304 (297 residues), 429.1 bits, see alignment E=4.6e-133 PF00296: Bac_luciferase" amino acids 17 to 297 (281 residues), 139.5 bits, see alignment E=8e-45

Best Hits

KEGG orthology group: None (inferred from 100% identity to mra:MRA_3125)

Predicted SEED Role

"L-fuco-beta-pyranose dehydrogenase (EC 1.1.1.122)" (EC 1.1.1.122)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.122

Use Curated BLAST to search for 1.1.1.122

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (334 amino acids)

>Rv3093c Hypothetical oxidoreductase (Mycobacterium tuberculosis H37Rv)
MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL
KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET
IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL
ASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGE
MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVA
VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR