Protein Info for Rv3092c in Mycobacterium tuberculosis H37Rv

Annotation: Probable conserved integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 transmembrane" amino acids 76 to 94 (19 residues), see Phobius details amino acids 165 to 187 (23 residues), see Phobius details amino acids 212 to 238 (27 residues), see Phobius details amino acids 269 to 297 (29 residues), see Phobius details PF05661: DUF808" amino acids 4 to 291 (288 residues), 383.3 bits, see alignment E=3.8e-119

Best Hits

KEGG orthology group: K09781, hypothetical protein (inferred from 100% identity to mtf:TBFG_13109)

Predicted SEED Role

"Membrane protein, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (306 amino acids)

>Rv3092c Probable conserved integral membrane protein (Mycobacterium tuberculosis H37Rv)
MSGGLFGLLDHVAVLARLAAASIDDIGAAAGRATAKAAGVVIDDTAVTPQYVHRITAERE
LPIIKRIAIGSVRNKLLLILPGALLLSQLVPWLLTPLLMLGATYLCYEGAEKVCGVIGGR
GHDAAPQVAERELVAGAIRTDFILSAEIMVIALNEVADQPFVPRLIVLVIVALVITAAVY
GVVAVIVQMDDVGLRLTQTASRFGQRIGGGLVAGMPKLLSALSAVGMGAMLWVGGHIVLV
GSDHLGWHAPYRLVHHLDDHLVGSAGGALTWLVSTAACAATGLVIGIVVVALVHLVCFRP
PRSRSL