Protein Info for Rv2821c in Mycobacterium tuberculosis H37Rv

Annotation: Conserved hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 236 TIGR02582: CRISPR type III-A/MTUBE-associated RAMP protein Csm3" amino acids 6 to 209 (204 residues), 243.5 bits, see alignment E=9.9e-77 PF03787: RAMPs" amino acids 13 to 208 (196 residues), 67.3 bits, see alignment E=1.3e-22

Best Hits

Swiss-Prot: 100% identical to CSM3_MYCTO: CRISPR system Cms endoribonuclease Csm3 (csm3) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

KEGG orthology group: K09002, hypothetical protein (inferred from 100% identity to mbo:Mb2845c)

Predicted SEED Role

"CRISPR-associated RAMP Csm3"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (236 amino acids)

>Rv2821c Conserved hypothetical protein (Mycobacterium tuberculosis H37Rv)
MTTSYAKIEITGTLTVLTGLQIGAGDGFSAIGAVDKPVVRDPLSRLPMIPGTSLKGKVRT
LLSRQYGADTETFYRKPNEDHAHIRRLFGDTEEYMTGRLVFRDTKLTNKDDLEARGAKTL
TEVKFENAINRVTAKANLRQMERVIPGSEFAFSLVYEVSFGTPGEEQKASLPSSDEIIED
FNAIARGLKLLELDYLGGSGTRGYGQVKFSNLKARAAVGALDGSLLEKLNHELAAV