Protein Info for Rv2638 in Mycobacterium tuberculosis H37Rv

Annotation: Conserved hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 148 TIGR00377: anti-anti-sigma factor" amino acids 29 to 136 (108 residues), 107.7 bits, see alignment E=1.3e-35 PF01740: STAS" amino acids 35 to 137 (103 residues), 73.3 bits, see alignment E=1.3e-24 PF13466: STAS_2" amino acids 44 to 124 (81 residues), 29.5 bits, see alignment E=7e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to mra:MRA_2667)

Predicted SEED Role

"Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (148 amino acids)

>Rv2638 Conserved hypothetical protein (Mycobacterium tuberculosis H37Rv)
MGLITTEPRSSPHPLSPRLVHELGDPHSTLRATTDGSGAALLIHAGGEIDGRNEHLWRQL
VTEAAAGVTAPGPLIVDVTGLDFMGCCAFAALADEAQRCRCRGIDLRLVSHQPIVARIAE
AGGLSRVLPIYPTVDTALGKGTAGPARC