Protein Info for Rv2554c in Mycobacterium tuberculosis H37Rv

Annotation: Conserved protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03652: RuvX
  • amino acids 23 to 155 (133 residues), 131.4 bits, E=1.4e-42
• TIGR00250: putative transcription antitermination factor YqgF
  • amino acids 25 to 155 (131 residues), 90.6 bits, E=4.3e-30

Best Hits

Swiss-Prot: 99% identical to YQGF_MYCBP: Putative pre-16S rRNA nuclease (BCG_2577c) from Mycobacterium bovis (strain BCG / Pasteur 1173P2)

KEGG orthology group: K07447, putative holliday junction resolvase [EC: 3.1.-.-] (inferred from 99% identity to mra:MRA_2583)

Predicted SEED Role

"Putative Holliday junction resolvase YggF"

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Protein Sequence (170 amino acids)

>Rv2554c Conserved protein (Mycobacterium tuberculosis H37Rv)
VVPAQHRPPDRPGDPAHDPGRGRRLGIDVGAARIGVACSDPDAILATPVETVRRDRSGKH
LRRLAALAAELEAVEVIVGLPRTLADRIGRSAQDAIELAEALARRVSPTPVRLADERLTT
VSAQRSLRQAGVRASEQRAVIDQAAAVAILQSWLDERLAAMAGTQEGSDA