Protein Info for Rv2084 in Mycobacterium tuberculosis H37Rv

Annotation: Hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 transmembrane" amino acids 99 to 117 (19 residues), see Phobius details

Best Hits

Swiss-Prot: 100% identical to Y2084_MYCTO: Uncharacterized protein MT2146 (MT2146) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

KEGG orthology group: None (inferred from 100% identity to mra:MRA_2100)

Predicted SEED Role

"FIG00821033: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (378 amino acids)

>Rv2084 Hypothetical protein (Mycobacterium tuberculosis H37Rv)
VSDDSSSAFDLICAEIERQLRGGELLMDAAAASELLLTVRYQLDTQPRPLVIVHGPLFQA
VKAARAQVYGRLIQLRHARCEVLDERWQLRPTGQRDVRALLIDVLNVLLAAITAAGVERA
YACAERRAMAAAVVAKNYRDALGVELQCNSVCRAAAEAIHALAHRTGATEDADCLPPVDV
IHADVTRRMHGEVATDVVAAGELVIAARHLLDPMPRGELSYGPLHEGGNAARKSVYRRLV
QLWQARRAVTDGDVDLRDARTLLTDLDSILREMRTAATIQQSGTAGDGGGGRRQDSRRRN
GPRRPARRGTSRGRRCAPRVAIGWHTPIGDPLAVEGVEEIGASLPGRESTPSDDGGSLHP
SGRPRRVHRRRWCGLGLC