Protein Info for Rv1710 in Mycobacterium tuberculosis H37Rv

Annotation: Possible segregation and condensation protein ScpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 231 TIGR00281: segregation and condensation protein B" amino acids 27 to 189 (163 residues), 111 bits, see alignment E=2.7e-36 PF04079: SMC_ScpB" amino acids 31 to 188 (158 residues), 158.6 bits, see alignment E=5.1e-51

Best Hits

KEGG orthology group: K06024, segregation and condensation protein B (inferred from 100% identity to mbo:Mb1737)

Predicted SEED Role

"Segregation and condensation protein B" in subsystem Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (231 amino acids)

>Rv1710 Possible segregation and condensation protein ScpB (Mycobacterium tuberculosis H37Rv)
VTEHMPEHDPSYGIPDIAEPAELDADELKRVLEALLLVIDTPVTADALAAATEQPVYRVA
AKLQLMADELTGRDSGIDLRHTSEGWRMYTRARFAPYVEKLLLDGARTKLTRAALETLAV
VAYRQPVTRARVSAVRGVNVDAVMRTLLARGLITEVGTDADTGAVTFATTELFLERLGLT
SLSELPDIAPLLPDVDTIDDLSESLDSEPRFIKLTGELASEQTLSFDVDRD