Protein Info for Rv1244 in Mycobacterium tuberculosis H37Rv

Annotation: Probable lipoprotein LpqZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF04069: OpuAC" amino acids 33 to 281 (249 residues), 72.5 bits, see alignment E=2.1e-24

Best Hits

KEGG orthology group: None (inferred from 99% identity to mbt:JTY_1279)

Predicted SEED Role

"Substrate-binding region of ABC-type glycine betaine transport system"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (286 amino acids)

>Rv1244 Probable lipoprotein LpqZ (Mycobacterium tuberculosis H37Rv)
VRITRILALLLAVLLAVSGVAGCSADTGDRHPELVVGSTPDSEAMLLAAIYVAALRSYGF
AAHAETAADPVAKLDSGAFTVVPAFTGQMLQTLQPDASVRSDAQVYRAIVSALPEGIAAG
DYTTAAEDKPALVVTQSTAKAWGGGDLSELPSHCRGLLVGRVAGAHTPAAVGPCRLPAPR
EFRNDATMFAALRAGQLVAAWTTTADPDIPADLIMLTDGKPALIRAENIVPLYRRNALTE
RQLLAVNEVAGVLDTTALIGMRRQVAAGADPAAVAAGWLAEHPLGR