Protein Info for Rv1128c in Mycobacterium tuberculosis H37Rv

Annotation: Conserved hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 451 PF02720: DUF222" amino acids 36 to 360 (325 residues), 383.1 bits, see alignment E=5.3e-119

Best Hits

Swiss-Prot: 100% identical to Y1128_MYCTU: Uncharacterized protein Rv1128c (Rv1128c) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

KEGG orthology group: None (inferred from 100% identity to mbb:BCG_1189c)

Predicted SEED Role

"FIG00829478: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (451 amino acids)

>Rv1128c Conserved hypothetical protein (Mycobacterium tuberculosis H37Rv)
MCSTREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCETARRQLPSVEHTLINQI
GEQSTEEELGGKLGLTLADRLRITRSEAKRRVAEAADLGQRRALTGEPLPPLLTATAKAQ
RHGLIGDGHVEVIRAFVHRLPSWVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLN
PDGDYTDEDRARRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAPGMCNPEQKA
PCVNGAPSKEQARRDTRSCPQRNHDALNAELRSLLTSGNLGQHNGLPASIIVTTTLKDLE
AAAGAGLTGGGTILPISDVIRLARHANHYLAIFDRGKALALYHTKRLASPAQRIMLYAKD
SGCSAPGCDVPGYYCEVHHVTPYAQCRNTDVNDLTLGCGGHHPLAERGWTTRKNAHGDTE
WLPPPHLDHGQPRVNTFHHPEKLLADDEGDP