Protein Info for Rv1061 in Mycobacterium tuberculosis H37Rv

Annotation: Conserved protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 287 PF13230: GATase_4" amino acids 1 to 250 (250 residues), 79.5 bits, see alignment E=2.1e-26 PF13522: GATase_6" amino acids 72 to 141 (70 residues), 29 bits, see alignment E=9.8e-11

Best Hits

KEGG orthology group: K07008, glutamine amidotransferase (inferred from 100% identity to mtb:TBMG_02925)

Predicted SEED Role

"glutamine amidotransferases, class-II"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (287 amino acids)

>Rv1061 Conserved protein (Mycobacterium tuberculosis H37Rv)
MCRLFGLHSGTDAVTATFWLLNASDSLAEQSRRNPDGTGLGVFDEHHQPRLHKQPIAAWQ
DADFATEAHELTGTTFVAHVRYATTGSLDIRNTHPFLQDGRIFAHNGVVEGLDVLDERLR
EVGADDLVLGQTDSERVFALITASIRARDGNESAGLIDALRWLAANVPIYAVNVLLSTAT
DVWALRYPESHELYILDRRGDGAPEFHLRSKRIRAHSTHLRERSSVVFATEPMDDNPRWR
LLDAGELVHVDAALRVNRSLVLPDPPRHPIRREDLSEPVLHAQHTSA