Protein Info for Rv1015c in Mycobacterium tuberculosis H37Rv

Annotation: 50S ribosomal protein L25 RplY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 215 PF01386: Ribosomal_L25p" amino acids 9 to 95 (87 residues), 82.8 bits, see alignment E=1.9e-27 TIGR00731: ribosomal protein bL25, Ctc-form" amino acids 9 to 181 (173 residues), 199.3 bits, see alignment E=2.1e-63 PF14693: Ribosomal_TL5_C" amino acids 103 to 181 (79 residues), 61.3 bits, see alignment E=9.3e-21

Best Hits

Swiss-Prot: 100% identical to RL25_MYCTO: 50S ribosomal protein L25 (rplY) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

KEGG orthology group: K02897, large subunit ribosomal protein L25 (inferred from 100% identity to mra:MRA_1023)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (215 amino acids)

>Rv1015c 50S ribosomal protein L25 RplY (Mycobacterium tuberculosis H37Rv)
MAKSASNQLRVTVRTETGKGASRRARRAGKIPAVLYGHGAEPQHLELPGHDYAAVLRHSG
TNAVLTLDIAGKEQLALTKALHIHPIRRTIQHADLLVVRRGEKVVVEVSVVVEGQAGPDT
LVTQETNSIEIEAEALSIPEQLTVSIEGAEPGTQLTAGQIALPAGVSLISDPDLLVVNVV
KAPTAEELEGEVAGAEEAEEAAVEAGEAEAAGESE