Protein Info for Rv0537c in Mycobacterium tuberculosis H37Rv

Annotation: Probable integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 transmembrane" amino acids 16 to 34 (19 residues), see Phobius details amino acids 46 to 66 (21 residues), see Phobius details amino acids 78 to 96 (19 residues), see Phobius details amino acids 110 to 128 (19 residues), see Phobius details amino acids 146 to 165 (20 residues), see Phobius details amino acids 185 to 209 (25 residues), see Phobius details amino acids 217 to 237 (21 residues), see Phobius details amino acids 262 to 279 (18 residues), see Phobius details amino acids 300 to 325 (26 residues), see Phobius details amino acids 334 to 352 (19 residues), see Phobius details amino acids 364 to 386 (23 residues), see Phobius details amino acids 409 to 431 (23 residues), see Phobius details

Best Hits

KEGG orthology group: None (inferred from 100% identity to mtc:MT0562)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (477 amino acids)

>Rv0537c Probable integral membrane protein (Mycobacterium tuberculosis H37Rv)
VGLSSDDTRRREVVRDLAAGALLIGALFFPWNLYFGFRIPDSSKTVFGLLLAVTSLSLAS
LAVTFAGRRSQLRLGLNVPYLLLVLAFVVFDAIQTIRLGGTVHVPGGVGPGGWLGITGAL
LSAQPALTGATTDEGSHSRWLRATQFLGYASMLGAALSTGFNLSWRVRYALEPAAGASGF
GKQNLAVIDTAVVYGVVALAAVLVASRWLLRPTAAEALSTVALGGSTLIAGSIVWSLPIG
REIDAFHGIAQNTSTAGVGYEGYLVWAAAAAMCAPLTLFRSPNAPPIDKTVWRAASRNGL
LLIAVWCLGSVAMRLTDLVVAVLLNYPFSRYDSMALAAFDLATAVLAIWLRFNMATEALP
ARLISSLCGLLCTFTVSRVIVGVVLAPRFQASSGGSAHPVYGNDLAQQITSTFDVVLCGL
ALSILAAAIVIGRLRQLPQPPHTPALSRPAGSPRIFRSAGSTHPVRPKIYRPPDHSS