Protein Info for Rv0419 in Mycobacterium tuberculosis H37Rv

Annotation: Possible lipoprotein peptidase LpqM

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 498 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details

Best Hits

KEGG orthology group: None (inferred from 100% identity to mbt:JTY_0428)

Predicted SEED Role

"POSSIBLE LIPOPROTEIN PEPTIDASE LPQM"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (498 amino acids)

>Rv0419 Possible lipoprotein peptidase LpqM (Mycobacterium tuberculosis H37Rv)
MHGRGRYRPLVRCVRPRRVAASVRTPIACLAAVVVIAGCTTVVDGRALSILNDPFRVGGL
PATNGPSGARPDAPAASGTVINTNNGAIDKLSLLSVNDIEDYWMAVYSESLKGTFRPVGK
LVSYDSNDPSSPIVCHIDTYQLVNAFFSSRCNLIAWDRGVFMAVAQEYFGDMSVNGVLAH
EFGHALQVMANLVTRKDPTIVREQQADCFAGVYLWWVAEGKSTRFTLSTADGLDHVLAGI
ITTRDPVMEADAENDDEHGSALDRVSAFQLGFINGTPACAAIDEDEVERRRGDLPTALRV
DASGNPETGEVGINEETLSTLMELMGKIFSPKNPPTLSYQPAGCPDAKPSPPAAYCPATN
TIVVDLPALARMGKVASAAEHSLPQGDDTSLSIVMSRYALAVQHERGLPMQSPWTALRTA
CLTGVAHRKMAVPIDLPSGQQLVLTAGDLDEAVSGLLTNRMVASDADGVSVPAGFTRIAA
FRAGVGGDMDACYARYPG